Faranak Rajabi

Faranak Rajabi

Ph. D. Candidate @UCSB

faranakrajabi@ucsb.edu

About Me:

I am a Ph.D. student in Mechanical Engineering at UC Santa Barbara's Computational Applied Science Laboratory (CASL), working under the supervision of Dr. Fredric Gibou and Dr. Jeff Moehlis.

My research develops computational methods for complex biological systems through distinct approaches: stochastic control strategies for neural oscillator networks with applications in Parkinson's disease treatment, Level Set Methods for solving high-dimensional Hamilton-Jacobi equations, and machine learning frameworks for biological systems. This work combines numerical methods, scientific computing, and machine learning to create novel tools for both theoretical understanding and practical applications.

Additionally, I'm pursuing an M.S. in Computer Science, strengthening my expertise in scientific computing and machine learning. Through this interdisciplinary approach, I aim to advance computational tools for understanding and controlling complex biological systems, with applications spanning from neuroscience to biotherapeutics.

Education

University of California, Santa Barbara

Ph.D. in Mechanical Engineering

Duration: Jan. 2022 – Present

Thesis: Advanced Computaional Methods for Biological Systems

Advisors: Dr. Fredric Gibou and Dr. Jeff Moehlis

Focus Areas:

  • Mathematical Modeling and Simulation
  • Scientific Software Development
  • Nonlinear Dynamics and Conrol

University of California, Santa Barbara

M.S. in Computer Science

Duration: Aug. 2023 – Present

Thesis: AI-Driven Drug Discovery

Advisors: Dr. Fredric Gibou

Focus Areas:

  • AI for Drug Discovery
  • ML for Signal Processing
  • Data Driven Control Design

Sharif University of Technology

B.S. in Aerospace Engineering

Duration: Sep. 2016 – July 2021

Thesis: Biomedical Applications of Mechanical Micropumps

Advisor: Dr. Kaveh Ghorbanian

Focus Areas:

  • Micro-Electro-Mechanical Systems(MEMS)
  • Microfluidics
  • Computational Fluid Dynamics

Research

Scientific Software Development

CASL-ForgeX: An advanced computational framework for solving nonlinear stochastic PDEs, specializing in Hamilton-Jacobi-Bellman equations using level set methods. Applications span neuroscience, engineering, finance, and machine learning.

Key features: Operator splitting techniques, high-dimensional PDE solving, uncertainty management, and multi-disciplinary applications
In Proceedings

Nonlinear Dynamics and Control for Neuroscience

Developing energy-efficient, event-based control strategies for neural networks using stochastic optimal control. Our approach incorporates system noise into deterministic models, achieving significant network desynchronization while minimizing energy consumption.

Impact: Enhanced battery life for implanted stimulators, robust performance across varying neural coupling strengths, and adaptive neurostimulation protocols

Micro-Fluidics and Computation

Investigating cell separation using active and passive methods, along with drug delivery applications in mechanical micropumps. Research focuses on enhancing separation efficiency and optimizing drug delivery mechanisms in.mechanisms in MEMS devices.

Applications: Biomedical devices, drug delivery systems, and cell manipulation techniques

Protein Aggregation Modeling

Developing novel computational models for protein aggregation in high-concentration biotherapeutics. Our approach bridges microscopic and macroscopic scales using continuum field representations and level-set methods to predict long-term stability in drug formulations.

Ongoing Research
Focus areas: monoclonal antibodies (mAb), protein stability, aggregation morphology, and multiscale modeling

Data-driven Control for Neuroscience

Developing machine learning-based approaches for adaptive Deep Brain Stimulation (DBS) in Parkinson's disease. Our research utilizes artificial neural networks to predict bursting events and modulate beta band rhythms in the basal ganglia.

Ongoing Research
Focus areas: local field potential analysis, predictive algorithms, neural networks for brain state prediction

AI in Drug Discovery

Implementing machine learning approaches to accelerate drug discovery pipelines. Focusing on deep learning models for molecular property prediction, protein-ligand interaction analysis, and drug candidate screening.

Ongoing Research
Focus areas: molecular modeling, binding affinity prediction, and computer-aided drug design

Teaching and Mentoring

Teaching

Introduction to Programming
Teaching Assistant 2022 – 2024

Instructed intensive Matlab programming course for STEM undergraduates

Quarters: Summer 2024, Spring/Summer 2023, Summer/Fall 2022
Mathematics of Engineering
Teaching Assistant 2022 – 2024

Instructed numerical simulation for engineering problems and ODEs using Matlab for Mechanical Engineering major undergraduate students

Quarters: Summer/Fall 2024, Fall 2023, Spring 2022
Basic Electronics and Circuits
Teaching Assistant & Lab Instructor Winter 2023

Taught engaging lectures in electronics circuits, mentored students, and facilitated group projects.

Quarter: Winter 2023
Dynamics
Teaching Assistant Summer 2023

Taught fundamental principles of motion and forces in engineering

Quarter: Summer 2023

Mentoring Positions

Career Mentor Fellow
American Physics Society Sept. 2023 – Present

Provide comprehensive career guidance to physics doctoral students, supporting their navigation through academic and non-academic career paths.

Graduate Division Mentor
UC Santa Barbara Sept. 2023 – Present

Support first-year and second-year doctoral students from diverse backgrounds, facilitating their academic and professional development.

Women in STEM Organization Mentor
UC Santa Barbara Oct. 2022 – Present

Mentor female undergraduate STEM students, providing academic support and fostering an inclusive learning environment.

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Publications

Conference Publications

  • Z. Rostami, F. Rajabi, and A. Shamloo, "Cell Separation by Using Active and Passive Methods Together," 4th International Conference on Innovative Technologies in Science, Engineering and Technology, Istanbul, Turkey, November 12, 2020.

  • F. Rajabi, A. Bakhshi, and G. Kazemi, "Drug Delivery Applications of Mechanical Micropumps," International Conference on Applied Researches in Science & Engineering, Amsterdam, Netherlands, January 10, 2021.

Papers Under Review

  • F. Rajabi, F. Gibou, and J. Moehlis, "Optimal Control for Stochastic Neural Oscillators," Under review at PLOS Computational Biology (PCOMPBIOL-D-24-01906).

  • F. Rajabi, J. Fingerman, A. Wang, J. Moehlis, and F. Gibou, "CASL-ForgeX: A Comprehensive Guide to Solving Deterministic and Stochastic Hamilton-Jacobi Equations," Under review at Computer Physics Communications.

Presentations

  • F. Rajabi, "A Level-Set Method Approach to Optimally Control Stochastic Neural Oscillators," Poster presented at the AAAS Pacific Division Conference 2024. [Poster]